Subcutaneous Panniculitis-like T-cell Lymphoma Complicated by Autoimmune Hemolytic Anemia: A Case Report
Keywords:
Subcutaneous Panniculitis-like T-cell Lymphoma, SPTCL, Autoimmune Hemolytic Anemia, AIHA, PanniculitisAbstract
A 36-year-old Thai female presented with generalized painful purplish skin nodules, fever, and other associated systemic symptoms for eight months. This report describes the clinical features, comprehensive laboratory findings, and the diagnosis of Subcutaneous Panniculitis-like T-cell Lymphoma (SPTCL), a rare type of T-cell lymphoma.
The diagnosis was confirmed by skin biopsy with immunohistochemical staining, showing a T-cell phenotype. Critically, the patient's laboratory profile revealed signs of severe complications: Autoimmune Hemolytic Anemia (AIHA) (confirmed by DAT Positive 3+).
Conclusion: The patient was subsequently treated with immunosuppressive therapy tailored to address the underlying lymphoma and AIHA, showing clinical improvement. This report highlights the importance of considering SPTCL in patients presenting with chronic panniculitis and systemic manifestations, and emphasizes the necessity of promptly recognizing life-threatening complications like autoimmune hemolytic anemia.
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